Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL1 | P55085 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | KDM4B | O94953 | 1/20 | 0.37 |
| ▸ | KDM5C | P41229 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3985925 | 0.73 | KDM4A (0.54) | F2RL1ALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL114028 | 0.73 | HIPK2 (0.41) | ALDH1A1MEN1KMT2AHIPK2MAPK1 | |
| SCHEMBL18701477 | 0.69 | EGLN1 (0.46) | ALDH1A1KDM4ELMNANOTUMKDM4A | |
| SCHEMBL10919818 | 0.69 | CYP2A6 (0.39) | ALDH1A1KDM4ELMNAHIPK2SMN1; SMN2 | |
| SCHEMBL3582119 | 0.69 | HIPK2 (0.36) | ALDH1A1HIPK2SMN1; SMN2 | |
| SCHEMBL1581968 | 0.67 | NOTUM (0.42) | F2RL1ALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL11102592 | 0.66 | CA12 (0.41) | HIPK2 | |
| SCHEMBL32810 | 0.66 | KDM4E (0.46) | ALDH1A1KDM4ELMNAMEN1GAA | |
| SCHEMBL29220900 | 0.65 | NOTUM (0.39) | ALDH1A1LMNAMAPTNOTUMHIPK2 | |
| SCHEMBL2687634 | 0.65 | ALDH1A1 (0.38) | ALDH1A1KDM4ELMNAMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 668 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332964-B | Synthesis method of bidentate pyrazolyl nitrogen heterocyclic palladium carbene compound | 西北大学 | 2024-05-24 | — | — | CN | claimed |
| CN-116332964-A | Synthesis method of bidentate pyrazolyl nitrogen heterocyclic palladium carbene compound | 西北大学 | 2023-06-27 | — | — | CN | claimed |
| US-20170327503-A1 | OPTIONALLY FUSED HETEROCYCLYL-SUBSTITUTED DERIVATIVES OF PYRIMIDINE USEFUL FOR THE TREATMENT OF INFLAMMATORY, METABOLIC, ONCOLOGIC AND AUTOIMMUNE DISEASES | NUEVOLUTION A/S (DK) | 2017-11-16 | — | — | US | claimed |
| CN-103102345-A | Aminoquinazoline derivative, salts thereof and application method | GUANGDONG HEC PHARMACEUTICAL | 2013-05-15 | — | — | CN | claimed |
| WO-2012082837-A1 | METHOD OF MAKING INDENO-FUSED NAPHTHOL MATERIALS | TRANSITIONS OPTICAL, INC. (US) | 2012-06-21 | — | — | WO | claimed |
| EP-2059305-A2 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | Novartis Ag (CH) | 2009-05-20 | — | — | EP | claimed |
| EP-1791825-B1 | BENZOYL-SUBSTITUTED SERINE AMIDES | BASF SE (DE) | 2008-09-17 | — | — | EP | claimed |
| WO-2008014307-A2 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | NOVARTIS AG (CH) | 2008-01-31 | — | — | WO | claimed |
| EP-1534684-B1 | INDAZOLE-AMINOACETONITRILE DERIVATIVES HAVING SPECIAL PESTICIDAL ACTIVITY | NOVARTIS AG (CH) | 2007-05-02 | — | — | EP | claimed |
| EP-1639058-A1 | PHOTOCHROMIC COMPOUNDS | TRANSITIONS OPTICAL, INC. (US) | 2006-03-29 | — | — | EP | claimed |
| EP-1115422-A4 | USE OF NON-PEPTIDYL COMPOUNDS FOR THE TREATMENT OF INSULIN RELATED AILMENTS | UNIV CURTIN TECH (AU) | 2003-01-29 | — | — | EP | claimed |
| US-20020151536-A1 | Combinations of peroxisome proliferator-activated receptor (PPAR) activator(s) and sterol absorption inhibitor(s) and treatments for vascular indications | SCHERING CORPORATION | 2002-10-17 | — | — | US | claimed |
| EP-1115422-A1 | USE OF NON-PEPTIDYL COMPOUNDS FOR THE TREATMENT OF INSULIN RELATED AILMENTS | CURTIN UNIVERSITY OF TECHNOLOGY (AU) | 2001-07-18 | — | — | EP | claimed |
| US-6166057-A | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 2000-12-26 | — | — | US | claimed |
| WO-2000016798-A1 | USE OF NON-PEPTIDYL COMPOUNDS FOR THE TREATMENT OF INSULIN RELATED AILMENTS | CURTIN UNIVERSITY OF TECHNOLOGY (AU) | 2000-03-30 | — | — | WO | claimed |
| EP-0874829-A1 | AMINO ACID DERIVATIVES, THE PREPARATION AND USE THEREOF AS ENDOTHELIN ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 1998-11-04 | — | — | EP | claimed |
| WO-1997012878-A1 | AMINO ACID DERIVATIVES, THE PREPARATION AND USE THEREOF AS ENDOTHELIN ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-10 | — | — | WO | claimed |
| US-4980348-A | HETEROANELLATED PHENYLGLYCINE-BETA-LACTAM ANTIBIOTICS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-12-25 | — | — | US | claimed |
| EP-0088276-B1 | COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL PREPARATIONS | BAYER AG (DE) | 1986-04-30 | — | — | EP | claimed |
| EP-0110259-A1 | 1,4-Dihydropyridines, processes for their preparation and their use in medicines | BAYER AG (DE) | 1984-06-13 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020151536-A1 | Combinations of peroxisome proliferator-activated receptor (PPAR) activator(s) and sterol absorption inhibitor(s) and treatments for vascular indications | PPARG, PPARA, PPARD | F2RL1 468/4885ALDH1A1 1058/4885KDM4E 3879/4885 |
| US-20170327503-A1 | OPTIONALLY FUSED HETEROCYCLYL-SUBSTITUTED DERIVATIVES OF PYRIMIDINE USEFUL FOR THE TREATMENT OF INFLAMMATORY, METABOLIC, ONCOLOGIC AND AUTOIMMUNE DISEASES | PPARD, PPARG, RORC | F2RL1 1969/4885ALDH1A1 1245/4885KDM4E 3194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.