Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.56 |
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | VNN1 | O95497 | 1/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983265 | 0.95 | POLB (0.56) | EPHX2LTA4HPOLBHRH3MEN1 | |
| SCHEMBL9269591 | 0.88 | LTA4H (0.52) | EPHX2LTA4HPOLBNLRP3 | |
| SCHEMBL10774498 | 0.86 | POLB (0.66) | EPHX2LTA4HPOLBMEN1KMT2A | |
| SCHEMBL27028196 | 0.85 | EPHX2 (0.60) | EPHX2LTA4HHRH3MEN1KMT2A | |
| SCHEMBL27237496 | 0.84 | MEN1 (0.66) | EPHX2LTA4HPOLBHRH3MEN1 | |
| SCHEMBL9266226 | 0.83 | LTA4H (0.56) | EPHX2LTA4HPOLBMEN1KMT2A | |
| SCHEMBL22323751 | 0.83 | EPHX2 (0.71) | EPHX2POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27028195 | 0.81 | POLB (0.58) | EPHX2LTA4HPOLBHRH3MEN1 | |
| SCHEMBL9269526 | 0.81 | POLB (0.56) | EPHX2LTA4HPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL6618984 | 0.80 | EPHX2 (0.48) | EPHX2LTA4HHRH3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111630031-B | Process for producing quinolin-4 (1H) -one derivative | 日本化药株式会社 | 2024-03-12 | — | — | CN | disclosed |
| US-11267787-B2 | Method for producing quinolin-4(1H)-one derivative | NIPPON KAYAKU CO., LTD (JP) | 2022-03-08 | — | — | US | disclosed |
| US-20210070710-A1 | METHOD FOR PRODUCING QUINOLIN-4(1H)-ONE DERIVATIVE | NIPPON KAYAKU CO., LTD. (JP) | 2021-03-11 | — | — | US | disclosed |
| CN-111630031-A | Process for producing quinolin-4 (1H) -one derivative | 日本化药株式会社 | 2020-09-04 | — | — | CN | disclosed |
| US-5403934-A | Heterocyclic compounds | BURROUGHS WELLCOME CO. (US) | 1995-04-04 | — | — | US | disclosed |
| WO-1991013873-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-19 | — | — | WO | disclosed |
| EP-0447164-A1 | Heterocyclic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11267787-B2 | Method for producing quinolin-4(1H)-one derivative | NQO2, AKR7A2, KEAP1 | EPHX2 1198/4885LTA4H 127/4885POLB 3585/4885 |
| US-20210070710-A1 | METHOD FOR PRODUCING QUINOLIN-4(1H)-ONE DERIVATIVE | NQO2, AKR7A2, KEAP1 | EPHX2 1198/4885LTA4H 127/4885POLB 3585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.