SCHEMBL9265705

SCHEMBL9265705

COC(=O)NCCN1CCC(n2cc(-c3ccc(F)cc3)c3cc(C)ccc32)CC1

nearest known ligand 0.79

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PLD2 O14939 1/20 0.41
PLD1 Q13393 1/20 0.41
ASH1L Q9NR48 1/20 0.39
CHRM3 P20309 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9273642 0.89 KDM1A (0.41) ASH1L
SCHEMBL9269584 0.86 CARM1 (0.43) ASH1L
SCHEMBL9272489 0.85 ABL1 (0.43) ASH1L
SCHEMBL9270580 0.85 SLC2A1 (0.43) ASH1L
SCHEMBL9287300 0.83 DRD2 (0.47) ASH1L
SCHEMBL9268386 0.82 ASH1L (0.43) ASH1LCHRM3
SCHEMBL9268846 0.82 ASH1L (0.42) ASH1L
SCHEMBL9272525 0.81 ASH1L (0.41) PLD2PLD1ASH1LCHRM3
SCHEMBL9274874 0.81 ASH1L (0.40) ASH1L
SCHEMBL9273497 0.79 ASH1L (0.44) ASH1L

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5445763-A Ferroelectricity; switching and/or display devices containing outer plates, electrodes, at least one polarizer and one alignment layer HOECHST AKTIENGESELLSCHAFT (DE) 1995-08-29 US disclosed
US-5393761-A Treatment of nervous system disorders H. LUNDBECK A/S (DK) 1995-02-28 US disclosed
EP-0470039-B1 Novel 3-arylindole and 3-arylindazole derivatives LUNDBECK & CO AS H (DK) 1994-12-07 EP disclosed
EP-0470039-A2 Novel 3-arylindole and 3-arylindazole derivatives H. LUNDBECK A/S (DK) 1992-02-05 EP disclosed