Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | CLK2 | P49760 | 1/20 | 0.65 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.65 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.65 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.65 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.65 |
| ▸ | TOP1 | P11387 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9785854 | 0.95 | KCNH2 (0.65) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL5570141 | 0.93 | KCNH2 (0.79) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| Water SCHEMBL9773975 | 0.92 | KCNH2 (0.78) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL9257732 | 0.89 | ALDH1A1 (0.68) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL5571094 | 0.88 | KCNH2 (0.74) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL5571237 | 0.87 | KCNH2 (0.76) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL5567734 | 0.86 | KCNH2 (0.74) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| Hydrochloric Acid SCHEMBL9774028 | 0.86 | KCNH2 (0.73) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| Water SCHEMBL9773903 | 0.86 | KCNH2 (0.73) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL9773824 | 0.84 | KCNH2 (0.79) | KCNH2KDM4EALDH1A1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5407932-A | Bactericides | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1995-04-18 | — | — | US | disclosed |
| EP-0393400-B1 | Novel quinolone derivatives, preparation processes thereof, and antibacterial agents containing the same | WAKUNAGA SEIYAKU KK (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5245037-A | Synthetic bactericides | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-09-14 | — | — | US | disclosed |
| EP-0393400-A1 | Novel quinolone derivatives, preparation processes thereof, and antibacterial agents containing the same | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1990-10-24 | — | — | EP | disclosed |