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SCHEMBL9266367

SCHEMBL9266367

CC(C)(C)OC(=O)N1CC2C(C1)C(c1ccccc1)(c1ccccc1)CCC2(F)F

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ RORC P51449 11/20 0.46
▸ USP30 Q70CQ3 1/20 0.43
▸ TSHR P16473 2/20 0.43
▸ ALOX15 P16050 1/20 0.43
▸ ATM Q13315 1/20 0.43
▸ GPR119 Q8TDV5 1/20 0.43
▸ TACR1 P25103 2/20 0.42
▸ NAMPT P43490 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9244693 0.88 TACR1 (0.49) RORCUSP30TSHRALOX15ATM
SCHEMBL8956952 0.88 TACR1 (0.49) RORCUSP30TSHRALOX15ATM
SCHEMBL8956761 0.82 TACR1 (0.52) RORCUSP30TSHRALOX15ATM
SCHEMBL8956775 0.82 TACR1 (0.54) RORCTSHRALOX15TACR1
SCHEMBL9270074 0.81 USP30 (0.45) RORCUSP30TSHRALOX15ATM
SCHEMBL9262375 0.81 USP30 (0.45) RORCUSP30TSHRALOX15ATM
SCHEMBL9003205 0.81 USP30 (0.45) RORCUSP30TSHRALOX15ATM
SCHEMBL9003033 0.81 USP30 (0.45) RORCUSP30TSHRALOX15ATM
SCHEMBL9003029 0.81 USP30 (0.45) RORCUSP30TSHRALOX15ATM
SCHEMBL8546697 0.80 TACR1 (0.68) RORCUSP30TSHRTACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5451601-A Perhydroisoindole derivatives and pharmaceutical compositions containing them RHONE-POULENC RORER S.A. (FR) 1995-09-19 — — US disclosed