Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9266428 | 1.00 | NPSR1 (0.43) | NPSR1TP53MAPTSMN1; SMN2EPHX1 | |
| SCHEMBL9262761 | 0.88 | ALDH1A1 (0.49) | TP53MAPTSMN1; SMN2EPHX1POLB | |
| SCHEMBL9262763 | 0.88 | ALDH1A1 (0.49) | TP53MAPTSMN1; SMN2EPHX1POLB | |
| SCHEMBL9269097 | 0.86 | DCUN1D1 (0.48) | EPHX1 | |
| SCHEMBL9271518 | 0.84 | EPHX1 (0.39) | TP53MAPTSMN1; SMN2EPHX1POLB | |
| SCHEMBL9271515 | 0.84 | EPHX1 (0.39) | TP53MAPTSMN1; SMN2EPHX1POLB | |
| SCHEMBL9270886 | 0.81 | TSHR (0.50) | TP53MAPTSMN1; SMN2EPHX1ALDH1A1 | |
| SCHEMBL9270884 | 0.81 | TSHR (0.50) | TP53MAPTSMN1; SMN2EPHX1ALDH1A1 | |
| SCHEMBL9267554 | 0.80 | ALDH1A1 (0.66) | NPSR1MAPTSMN1; SMN2POLBLMNA | |
| SCHEMBL9267562 | 0.80 | ALDH1A1 (0.66) | NPSR1MAPTSMN1; SMN2POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420164-A | Enzyme inhibitors | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-05-30 | — | — | US | disclosed |