Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9270886 | 1.00 | TSHR (0.50) | TSHRRAB9ASMN1; SMN2EPHX1ALDH1A1 | |
| SCHEMBL9271518 | 0.84 | EPHX1 (0.39) | SMN1; SMN2EPHX1ALDH1A1CYP3A4KMT2A | |
| SCHEMBL9271515 | 0.84 | EPHX1 (0.39) | SMN1; SMN2EPHX1ALDH1A1CYP3A4KMT2A | |
| SCHEMBL9269097 | 0.84 | DCUN1D1 (0.48) | EPHX1 | |
| SCHEMBL9266428 | 0.81 | NPSR1 (0.43) | SMN1; SMN2EPHX1ALDH1A1MEN1KMT2A | |
| SCHEMBL9266431 | 0.81 | NPSR1 (0.43) | SMN1; SMN2EPHX1ALDH1A1MEN1KMT2A | |
| SCHEMBL9262761 | 0.80 | ALDH1A1 (0.49) | RAB9ASMN1; SMN2EPHX1ALDH1A1MEN1 | |
| SCHEMBL9262763 | 0.80 | ALDH1A1 (0.49) | RAB9ASMN1; SMN2EPHX1ALDH1A1MEN1 | |
| SCHEMBL9272164 | 0.80 | UBE2M (0.42) | — | |
| SCHEMBL9272166 | 0.80 | UBE2M (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420164-A | Enzyme inhibitors | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-05-30 | — | — | US | disclosed |