SCHEMBL9267477

SCHEMBL9267477

O=S(=O)(c1ccc(Cl)cc1)C1(O)C=CC(c2ccccc2)=CC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSEN1 P49768 2/20 0.41
PSEN2 P49810 2/20 0.41
APH1B Q8WW43 2/20 0.41
NCSTN Q92542 2/20 0.41
APH1A Q96BI3 2/20 0.41
PSENEN Q9NZ42 2/20 0.41
EEF2K O00418 1/20 0.40
HSD11B1 P28845 1/20 0.38
ALDH1A1 P00352 3/20 0.37
ADAMTS5 Q9UNA0 3/20 0.36
MMP2 P08253 2/20 0.36
APP P05067 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
MMP1 P03956 1/20 0.34
MMP9 P14780 1/20 0.34
MMP8 P22894 1/20 0.34
MMP13 P45452 1/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9486786 0.84 PSEN1 (0.43) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL6027307 0.79 TSHR (0.31) MEN1KMT2APOLBGAASMN1; SMN2
SCHEMBL3889473 0.77 USP2 (0.31) ALDH1A1MEN1KMT2ASMN1; SMN2PTGS2
SCHEMBL27811296 0.77 PPARG (0.36) ALDH1A1MEN1KMT2AMAPT
SCHEMBL10533333 0.70 CES2 (0.40) ALDH1A1MEN1KMT2AL3MBTL1MAPT
SCHEMBL5321336 0.70 SMN1; SMN2 (0.34) MMP2CA1CA2MMP1MMP9
SCHEMBL6177001 0.69
SCHEMBL5390125 0.69 MEN1 (0.30) MEN1KMT2A
SCHEMBL222999 0.68 ALDH1A1 (0.31) ALDH1A1
SCHEMBL447640 0.68 TSHR (0.31) MMP2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110382761-A The manufacturing method of non-woven fabrics 住友化学株式会社 2019-10-25 CN disclosed
CN-110352272-A Non-woven fabrics 住友化学株式会社 2019-10-18 CN disclosed
EP-3533819-A1 METHOD FOR PRODUCING AROMATIC POLYSULFONE Sumitomo Chemical Company, Ltd. (JP) 2019-09-04 EP disclosed
CN-109890871-A Method for producing aromatic polysulfone 住友化学株式会社 2019-06-14 CN disclosed
CN-109328207-A Aromatic series polysulfones and aromatic series polysulfone compositions 住友化学株式会社 2019-02-12 CN disclosed
CN-109312068-A aromatic polysulfone and aromatic polysulfone composition 住友化学株式会社 2019-02-05 CN disclosed
CN-102510772-A Aromatic polysulfone resin porous membrane SUMITOMO CHEMICAL CO 2012-06-20 CN disclosed
EP-0682560-A1 POLYMER POROUS STRUCTURE AND PROCESS NORTH WEST WATER GROUP PLC (GB) 1995-11-22 EP disclosed
WO-1994017905-A1 POLYMER POROUS STRUCTURE AND PROCESS NORTH WEST WATER GROUP PLC. (GB) 1994-08-18 WO disclosed