Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | PARP1 | P09874 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5696772 | 0.91 | ALDH1A1 (0.73) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL3968491 | 0.80 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL3960715 | 0.80 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL3960707 | 0.80 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL3968494 | 0.80 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL5358355 | 0.80 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL5016632 | 0.79 | TSHR (0.73) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL16714724 | 0.79 | TSHR (0.73) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL25334940 | 0.78 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL11470219 | 0.78 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995029155-A1 | NOVEL ANTITUMOUR COMPOUNDS WITH ANTIMITOTIC ACTIVITY | PHARMACIA AB (SE) | 1995-11-02 | — | — | WO | disclosed |