SCHEMBL9268

SCHEMBL9268

O=COCc1ccccc1[N+](=O)[O-]

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.55
TSHR P16473 1/20 0.55
HTT P42858 2/20 0.54
HPGD P15428 1/20 0.50
MAOB P27338 1/20 0.49
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
RECQL P46063 1/20 0.44
HTR1A P08908 1/20 0.44
ADRA1D P25100 1/20 0.44
ADRA1A P35348 1/20 0.44
ADRA1B P35368 1/20 0.44
LMNA P02545 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
KMT2A Q03164 2/20 0.43
CA12 O43570 1/20 0.43
CA9 Q16790 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8539483 0.87 ALDH1A1 (0.56) ALDH1A1TSHRHTTHPGDMAOB
SCHEMBL10389234 0.84 ALDH1A1 (0.53) ALDH1A1TSHRHTTHPGDMAOB
SCHEMBL1967927 0.84 ALDH1A1 (0.53) ALDH1A1TSHRHTTHPGDMAOB
SCHEMBL14443263 0.82 ALDH1A1 (0.41) ALDH1A1TSHRHTTHPGDMAOB
SCHEMBL1060760 0.81 ALDH1A1 (0.50) ALDH1A1TSHRHTTHPGDMAOB
SCHEMBL77922 0.81 ALDH1A1 (0.62) ALDH1A1TSHRHTTHPGDMAOB
SCHEMBL28456222 0.80 ALDH1A1 (0.52) ALDH1A1TSHRHTTHPGDMAOB
SCHEMBL5067951 0.80 TDP1 (0.45) ALDH1A1TSHRHTTHPGDNPC1
SCHEMBL6324823 0.79 ALDH1A1 (0.51) ALDH1A1TSHRHTTHPGDMAOB
SCHEMBL28424497 0.79 ALDH1A1 (0.48) ALDH1A1TSHRHTTHPGDMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6353 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11891668-B2 Methods for generating therapeutic delivery platforms THE UNIVERSITY OF KANSAS (US) 2024-02-06 US claimed
CN-116396296-A Preparation method of ertapenem 武汉瑞晟药业有限公司 2023-07-07 CN claimed
EP-4140988-A1 L-VALINATE OF HYDROXYPROPYLTHIAZOLIDINE CARBOXAMIDE DERIVATIVE AND SALT FORM, CRYSTAL POLYMORPH THEREOF Merck Serono S.A. (CH) 2023-03-01 EP claimed
US-11235330-B2 Hydrogel membrane and methods for selective retrieval of microbial targets KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) 2022-02-01 US claimed
EP-3053944-B1 METHOD FOR PRODUCING POLYALKYLENE GLYCOL DERIVATIVE HAVING AMINO GROUP AT END, POLYMERIZATION INITIATOR FOR USE IN THE SAME, AND ALCOHOL COMPOUND AS RAW MATERIAL FOR THE POLYMERIZATION INITIATOR SHINETSU CHEMICAL CO (JP) 2021-10-06 EP claimed
US-20210300932-A1 CYCLIC PEPTIDES TARGETING ALPHA-4-BETA-7 INTEGRIN ZEALAND PHARMA A/S (DK) 2021-09-30 US claimed
US-11072616-B2 Cyclic peptides targeting alpha-4-beta-7 integrin UNIVERSITE DE MONTREAL (CA) 2021-07-27 US claimed
EP-3720854-B1 SOLID PHASE SYNTHESIS OF NIR FLUORESCENT PROBE BRACCO IMAGING SPA (IT) 2021-04-21 EP claimed
CN-107002293-B Sequencing by synthesis using pulsed readout optics 艾比斯生物科学公司 2020-12-08 CN claimed
EP-3470399-B1 METHOD FOR PRODUCING OPTICALLY ACTIVE VALERIC ACID DERIVATIVE DAIICHI SANKYO CO LTD (JP) 2020-11-04 EP claimed
EP-0292806-A2 Substituted vinyl cephalosporins, process for their preparation and their use as medicines BAYER AG (DE) 1988-11-30 EP claimed
EP-0268963-A1 Benzazolylthio-carbapenem antibiotics BAYER AG (DE) 1988-06-01 EP claimed
EP-0247431-A1 Substituted 6-hydroxymethylcarbapenem antibiotics, process for their preparation and their use BAYER AG (DE) 1987-12-02 EP claimed
US-4581170-A N-hydroxyl protecting groups and process and intermediates for the preparation of 3-acylamino-1-hydroxy-2-azetidinones E. R. SQUIBB & SONS, INC. (US) 1986-04-08 US claimed
EP-0170280-A1 Novel intermediates and process for the preparation of 3-acylamino-1-hydroxy-2-azetidinones E.R. Squibb & Sons, Inc. (US) 1986-02-05 EP claimed
US-4460507-A Process for the preparation of thienamycin MERCK & CO., INC. (US) 1984-07-17 US claimed
US-4341705-A Thienamycin derivatives MERCK & CO., INC. (US) 1982-07-27 US claimed
US-4272432-A Claudogenic-interceptive nonapeptide AMERICAN HOME PRODUCTS CORPORATION (US) 1981-06-09 US claimed
US-4146633-A ANTIBIOTICS, BACTERICIDES MERCK & CO., INC. (US) 1979-03-27 US claimed
US-4009159-A PENICILLINS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-02-22 US claimed