Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9270224 | 0.83 | HPGD (0.42) | PTGS1ALDH1A1MAPTHTTMEN1 | |
| SCHEMBL9275446 | 0.83 | PDE4B (0.57) | ALDH1A1MAPTHTTMEN1LMNA | |
| SCHEMBL9274767 | 0.83 | ME2 (0.52) | PTGS1MAPTMEN1KMT2APDE4B | |
| SCHEMBL9275486 | 0.82 | PDE4B (0.61) | ALDH1A1MAPTHTTMEN1LMNA | |
| SCHEMBL9274969 | 0.81 | MEN1 (0.42) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL9270824 | 0.81 | PDE4B (0.41) | ALDH1A1MAPTHTTMEN1LMNA | |
| SCHEMBL9272045 | 0.81 | PTGS1 (0.52) | PTGS1ALDH1A1LMNAHPGDPTGS2 | |
| SCHEMBL9271698 | 0.74 | EDNRB (0.43) | PTGS1MAPTHTTMEN1KMT2A | |
| SCHEMBL9270914 | 0.73 | MAPT (0.44) | ALDH1A1MAPTHTTMEN1LMNA | |
| SCHEMBL30320677 | 0.72 | ME2 (0.57) | PTGS1ALDH1A1MAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423482-B1 | 5H-furan-2-one derivatives | BAYER AG (DE) | 1995-01-11 | — | — | EP | claimed |