Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MITF | O75030 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9275446 | 0.96 | PDE4B (0.57) | PDE4BMAPTALDH1A1MITFHTT | |
| SCHEMBL9270224 | 0.84 | HPGD (0.42) | PDE4BMAPTALDH1A1MITFHTT | |
| SCHEMBL9274767 | 0.84 | ME2 (0.52) | PDE4BMAPTPTGS2TP53RAB9A | |
| SCHEMBL9268228 | 0.82 | PTGS1 (0.50) | PDE4BMAPTALDH1A1MITFHTT | |
| SCHEMBL9270824 | 0.82 | PDE4B (0.41) | PDE4BMAPTALDH1A1MITFHTT | |
| SCHEMBL9274969 | 0.82 | MEN1 (0.42) | PDE4BMAPTALDH1A1MITFHTT | |
| SCHEMBL9274675 | 0.80 | HDAC4 (0.50) | MAPTALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL592300 | 0.79 | PTGS2 (0.65) | PDE4BMAPTALDH1A1MITFHTT | |
| SCHEMBL9272045 | 0.78 | PTGS1 (0.52) | ALDH1A1PTGS2KDM4ELMNAHPGD | |
| SCHEMBL9269106 | 0.78 | NOTUM (0.45) | MAPTCYP1A2SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423482-B1 | 5H-furan-2-one derivatives | BAYER AG (DE) | 1995-01-11 | — | — | EP | claimed |
| US-5140013-A | Shelf life; polymerization inhibition; nontoxic; side effects reduction | UNIVERSITE LAVAL (CA) | 1992-08-18 | — | — | US | disclosed |
| WO-1991008775-A2 | MALEIC ANHYDRIDE DERIVATIVES USED AS CONJUGATION AGENTS OF ANTI-TUMOR AGENTS ON DESIRED CARRIERS | UNIVERSITE LAVAL (CA) | 1991-06-27 | — | — | WO | disclosed |