SCHEMBL9268395

SCHEMBL9268395

C1=CCC(c2cccc3c2ccc2ccccc23)=C1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 3/20 0.48
ALDH1A1 P00352 7/20 0.41
HSD17B10 Q99714 6/20 0.41
TSHR P16473 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
CYP2A6 P11509 2/20 0.41
PAX8 Q06710 1/20 0.37
HPGD P15428 5/20 0.37
CYP1A2 P05177 5/20 0.37
HIF1A Q16665 4/20 0.37
MAPK1 P28482 4/20 0.37
LMNA P02545 2/20 0.37
MEN1 O00255 1/20 0.37
USP2 O75604 1/20 0.37
TP53 P04637 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
ALOX12 P18054 1/20 0.37
CYP2C19 P33261 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5696379 0.91 SLC6A3 (0.41) ALDH1A1HSD17B10TSHRTDP1CYP2A6
SCHEMBL6242909 0.89 SLC6A3 (0.40) ALDH1A1HSD17B10TSHRTDP1CYP2A6
SCHEMBL28204063 0.86 SLC6A3 (0.38) ALDH1A1HSD17B10CYP2A6HPGDCYP1A2
SCHEMBL7771419 0.82 ALDH1A1 (0.40) HPRT1ALDH1A1HSD17B10TSHRTDP1
SCHEMBL28502880 0.80 HPRT1 (0.58) HPRT1ALDH1A1HSD17B10TSHRTDP1
SCHEMBL9671120 0.79 DNMT1 (0.40) HPRT1ALDH1A1HSD17B10TSHRTDP1
SCHEMBL2045558 0.79 TSHR (0.46) HPRT1ALDH1A1HSD17B10TSHRTDP1
SCHEMBL146502 0.79 ALDH1A1 (0.40) ALDH1A1HSD17B10TSHRHPGDCYP1A2
SCHEMBL17025979 0.78 ALDH1A1 (0.39) ALDH1A1HSD17B10TSHRHPGDCYP1A2
SCHEMBL28006187 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-208809266-U It is a kind of to continue heating and moistening atomising device 倪益益 2019-05-03 CN claimed
CN-207270532-U A kind of three-dimensional visible noctilucence transfusion device 赵齐美 2018-04-27 CN claimed
CN-206311458-U A kind of test device of Corrosion Reinforcement area of section 深圳大学 2017-07-07 CN claimed
CN-106923993-A Multi-functional assisted transfusion case 李平 2017-07-07 CN claimed
CN-106596316-A Device and method for testing area of cross section of rusted reinforcing steel bar 深圳大学 2017-04-26 CN claimed
CN-205411836-U Infusion dropping speed detection monitoring device 李平 2016-08-03 CN claimed
CN-208809266-U It is a kind of to continue heating and moistening atomising device 倪益益 2019-05-03 CN disclosed
CN-208660040-U The perfusion tube that intelligently can shut off and alarm 许莹莹 2019-03-29 CN disclosed
CN-208660040-U The perfusion tube that intelligently can shut off and alarm 许莹莹 2019-03-29 CN disclosed
CN-109498898-A A kind of infusion alarm based on weight method wireless sensor technology 昆明理工大学 2019-03-22 CN disclosed
CN-207203175-U A kind of infrared detecting device for being used to infuse 湖南新云医疗装备工业有限公司 2018-04-10 CN disclosed
CN-107596495-A Automatic infusion device 郝立辉 2018-01-19 CN disclosed
CN-206311458-U A kind of test device of Corrosion Reinforcement area of section 深圳大学 2017-07-07 CN disclosed
CN-205411836-U Infusion dropping speed detection monitoring device 李平 2016-08-03 CN disclosed
US-5434264-A α,α-disubstituted aromatics and heteroaromatics as cognition enhancers THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1995-07-18 US disclosed
US-5300642-A α, α-disubstituted aromatics and heteroaromatics as cognition enhancers THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1994-04-05 US disclosed
EP-0311010-B1 Alpha,Alpha-disubstituted aromatics and heteroaromatics as cognition enhancers DU PONT MERCK PHARMA (US) 1994-02-02 EP disclosed
EP-0532054-A1 Process for preparing alpha,alpha-disubstituted aromatics and heteroaromatics as cognition enhancers THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1993-03-17 EP disclosed
US-5173489-A α,α-disubstituted aromatics and heteroaromatics as cognition enhancers THE DUPONT MERCK PHARMACEUTICAL CO. (US) 1992-12-22 US disclosed
EP-0311010-A2 Alpha,Alpha-disubstituted aromatics and heteroaromatics as cognition enhancers THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1989-04-12 EP disclosed