Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.55 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.55 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.55 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.55 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28152490 | 0.96 | ALOX5 (0.67) | NPC1MAPTALOX5RAB9AMEN1 | |
| SCHEMBL7791330 | 0.91 | RAB9A (0.62) | NPC1MAPTALOX5RAB9AMEN1 | |
| SCHEMBL1777985 | 0.89 | ALOX5 (0.60) | NPC1MAPTALOX5RAB9AMEN1 | |
| SCHEMBL1779167 | 0.89 | ALOX5 (0.59) | NPC1MAPTALOX5RAB9AMEN1 | |
| SCHEMBL10236929 | 0.85 | RAB9A (0.82) | NPC1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL11350421 | 0.85 | RAB9A (0.82) | NPC1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL31556116 | 0.84 | MAOB (0.58) | NPC1MAPTALOX5RAB9AMEN1 | |
| SCHEMBL10615958 | 0.84 | NPC1 (0.58) | NPC1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL7405217 | 0.84 | F2 (0.65) | NPC1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL6162284 | 0.83 | SMN1; SMN2 (0.79) | NPC1MAPTRAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5464865-A | Enzyme inhibitors as antiinflammatory agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1995-11-07 | — | — | US | disclosed |
| US-4682193-A | HEAT SENSITIVE, STORAGE STABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 1987-07-21 | — | — | US | disclosed |