Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | GAPDH | P04406 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9267526 | 0.82 | STAT3 (0.45) | HTTKMT2ASTAT3KDM4EALDH1A1 | |
| SCHEMBL9265456 | 0.81 | STAT3 (0.42) | HTTKMT2AGSK3BSTAT3KDM4E | |
| SCHEMBL9044625 | 0.78 | HTT (0.41) | MAOBHTTKMT2AMEN1HSP90AA1 | |
| SCHEMBL583970 | 0.78 | ADRB2 (0.54) | GSK3BSTAT3KDM4EALDH1A1ADRB2 | |
| SCHEMBL10772266 | 0.78 | STAT3 (0.46) | MAOBHTTKMT2AMEN1GSK3B | |
| SCHEMBL1345409 | 0.77 | ADRB2 (0.43) | HTTGSK3BKDM4EALDH1A1HPGD | |
| SCHEMBL9502058 | 0.77 | ADRB2 (0.48) | HTTGSK3BKDM4EALDH1A1HPGD | |
| SCHEMBL9261876 | 0.76 | STAT3 (0.47) | HTTKMT2AMEN1GSK3BSTAT3 | |
| SCHEMBL9270695 | 0.76 | KMT2A (0.57) | HTTKMT2AMEN1STAT3KDM4E | |
| SCHEMBL9501129 | 0.75 | ADRB2 (0.51) | HTTKMT2AMEN1GSK3BSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5407932-A | Bactericides | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1995-04-18 | — | — | US | disclosed |
| EP-0393400-B1 | Novel quinolone derivatives, preparation processes thereof, and antibacterial agents containing the same | WAKUNAGA SEIYAKU KK (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5245037-A | Synthetic bactericides | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-09-14 | — | — | US | disclosed |
| EP-0393400-A1 | Novel quinolone derivatives, preparation processes thereof, and antibacterial agents containing the same | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1990-10-24 | — | — | EP | disclosed |