Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | STAT3 | P40763 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL263981 | 0.95 | STAT3 (0.48) | ADRB2STAT3HTTKMT2AKCNH2 | |
| SCHEMBL30181222 | 0.94 | ADRB2 (0.50) | ADRB2STAT3HTTKMT2AKCNH2 | |
| SCHEMBL5507636 | 0.94 | ADRB2 (0.50) | ADRB2STAT3HTTKMT2AKCNH2 | |
| SCHEMBL1344567 | 0.92 | HSD17B10 (0.46) | ADRB2STAT3HTTKMT2AKCNH2 | |
| SCHEMBL9501304 | 0.91 | GSK3B (0.49) | ADRB2STAT3HTTKMT2AKCNH2 | |
| SCHEMBL7584135 | 0.88 | ADRB2 (0.47) | ADRB2STAT3HTTKMT2AKCNH2 | |
| SCHEMBL8741004 | 0.85 | ADRB2 (0.47) | ADRB2STAT3HTTKMT2AKCNH2 | |
| SCHEMBL1346839 | 0.85 | ADRB2 (0.55) | ADRB2STAT3HTTKMT2AKCNH2 | |
| SCHEMBL9148194 | 0.85 | ADRB2 (0.55) | ADRB2STAT3HTTKMT2AKCNH2 | |
| SCHEMBL4306583 | 0.85 | KMT2A (0.60) | ADRB2STAT3HTTKMT2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2028157-A | — | — | None | — | — | JP | disclosed |
| US-20230058189-A1 | QUINOLIN-4-ONE AND 4(1H)-CINNOLINONE COMPOUNDS AND METHODS OF USING SAME | Frequency Therapeutics, Inc. (US) | 2023-02-23 | — | — | US | disclosed |
| EP-0312085-B1 | NOVEL QUINOLINE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND ANTIBACTERIAL AGENT CONTAINING THEM | Dainippon Pharmaceutical Co., Ltd. (JP) | 1993-05-12 | — | — | EP | disclosed |
| US-5164392-A | Active against streptococci and staphylococci | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1992-11-17 | — | — | US | disclosed |
| US-5013841-A | Oxo quinoline derivatives | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1991-05-07 | — | — | US | disclosed |
| JP-H0228157-A | NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVE, ITS ESTER AND SALT THEREOF | DAINIPPON PHARMACEUT CO LTD | 1990-01-30 | — | — | JP | disclosed |
| EP-0312085-A2 | Novel quinoline derivatives, processes for preparation thereof and antibacterial agent containing them | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-04-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230058189-A1 | QUINOLIN-4-ONE AND 4(1H)-CINNOLINONE COMPOUNDS AND METHODS OF USING SAME | DCX, NES, MCL1 | ADRB2 4044/4885STAT3 499/4885HTT 3286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.