SCHEMBL9270503

SCHEMBL9270503

CC(O)c1cccc(Oc2ccccc2)n1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 4/20 0.44
F10 P00742 4/20 0.44
PRSS1 P07477 1/20 0.44
PRSS2 P07478 1/20 0.44
PRSS3 P35030 1/20 0.44
ST14 Q9Y5Y6 1/20 0.44
ALDH1A1 P00352 2/20 0.42
HTT P42858 2/20 0.42
POLB P06746 1/20 0.40
MAP4K4 O95819 1/20 0.39
JAK2 O60674 1/20 0.39
JAK1 P23458 1/20 0.39
JAK3 P52333 1/20 0.39
HPGD P15428 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
MAPT P10636 2/20 0.38
MAPK1 P28482 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
CYP1A2 P05177 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9818071 1.00 F2 (0.44) F2F10PRSS1PRSS2PRSS3
SCHEMBL10548446 1.00 F2 (0.44) F2F10PRSS1PRSS2PRSS3
SCHEMBL17693892 0.86 F2 (0.42) F2F10PRSS1PRSS2PRSS3
SCHEMBL11360231 0.86 F2 (0.46) F2F10PRSS1PRSS2PRSS3
SCHEMBL9818057 0.85 HTT (0.45) F2F10PRSS1PRSS2PRSS3
SCHEMBL11391658 0.85 MEN1 (0.45) F2F10PRSS1PRSS2PRSS3
SCHEMBL9818055 0.85 HTT (0.45) F2F10PRSS1PRSS2PRSS3
SCHEMBL11387393 0.83 F2 (0.40) F2F10PRSS1PRSS2PRSS3
SCHEMBL11249422 0.83 F2 (0.40) F2F10PRSS1PRSS2PRSS3
SCHEMBL11467976 0.82 LMNA (0.42) F2F10PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0476708-B1 (Trifluoromethyl)vinyl pyrethroid derivatives, their use as pesticides, process for their preparation, and intermediates of that process ROUSSEL UCLAF (FR) 1995-11-08 EP claimed
US-4661488-A Pyrimidine substituted-2,2-dimethylcyclopropane carboxylates useful for combating insect and acarine pests at a locus IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-04-28 US claimed
EP-0162538-A2 Cyclopropane derivates IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-11-27 EP claimed
JP-60136562-A None JP disclosed
JP-4049280-A None JP disclosed
EP-0476708-B1 (Trifluoromethyl)vinyl pyrethroid derivatives, their use as pesticides, process for their preparation, and intermediates of that process ROUSSEL UCLAF (FR) 1995-11-08 EP disclosed
EP-0476708-A1 (Trifluoromethyl)vinyl pyrethroid derivatives, their use as pesticides, process for their preparation, and intermediates of that process ROUSSEL UCLAF (FR) 1992-03-25 EP disclosed
JP-H0449280-A ESTER COMPOUND, ITS PRODUCTION AND INSECTICIDAL AND MITICIDAL AGENT CONTAINING THE COMPOUND AS ACTIVE COMPONENT SUMITOMO CHEM CO LTD 1992-02-18 JP disclosed
US-5089511-A Trifluoromethylvinyl compounds ROUSSEL UCLAF (FR) 1992-02-18 US disclosed
EP-0298590-B1 HALOGENATED ESTERS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-12-11 EP disclosed
US-4920231-A Reacting with trifluoroacetic acid with halovinyl compound in presence of cuprous salt ROUSSEL UCLAF (FR) 1990-04-24 US disclosed
JP-S60136562-A 1-(6-PHENOXY-2-PYRIDYL)ETHANOL AND MANUFACTURE CIBA GEIGY AG 1985-07-20 JP disclosed
EP-0112293-A1 Isomers of 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane-carboxylic-acid-alpha-methyl-(6-phenoxy-2-picolyl) ester, process for their preparation and their use as pesticides CIBA-GEIGY AG (CH) 1984-06-27 EP disclosed
US-4447613-A Pyridyl esters and thiolesters of aminoalkanoic acids ZOECON CORPORATION (US) 1984-05-08 US disclosed
US-4323574-A INSECTICIDES, PESTICIDES ZOECON CORPORATION (US) 1982-04-06 US disclosed
US-4269981-A Certain pyridylmethyl esters of formamido-lower-alkanoates and derivatives thereof ZOECON CORPORATION (US) 1981-05-26 US disclosed
US-4248875-A INSECTICIDES, MITICIDES ZOECON CORPORATION (US) 1981-02-03 US disclosed
US-4247701-A Certain pesticidal substituted amino lower-alkanoates or lower-alkano-thioates containing pyridyl in the ester portion ZOECON CORPORATION (US) 1981-01-27 US disclosed
US-4226872-A Pyridyl esters of α-substituted amino acids ZOECON CORPORATION (US) 1980-10-07 US disclosed
US-4224330-A Esters and thiolesters of benzothienyl acids ZOECON CORPORATION (US) 1980-09-23 US disclosed