Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 4/20 | 0.41 |
| ▸ | F10 | P00742 | 4/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 9/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10548446 | 0.82 | F2 (0.44) | LMNAF2F10PRSS1PRSS2 | |
| SCHEMBL9818071 | 0.82 | F2 (0.44) | LMNAF2F10PRSS1PRSS2 | |
| SCHEMBL9270503 | 0.82 | F2 (0.44) | LMNAF2F10PRSS1PRSS2 | |
| SCHEMBL11360231 | 0.82 | F2 (0.46) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL22481201 | 0.80 | ADRB1 (0.56) | LMNA | |
| SCHEMBL23888635 | 0.80 | CYP3A4 (0.44) | LMNA | |
| SCHEMBL17693892 | 0.78 | F2 (0.42) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL8972394 | 0.76 | F2 (0.43) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL11387393 | 0.76 | F2 (0.40) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL11249422 | 0.76 | F2 (0.40) | F2F10PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4226872-A | Pyridyl esters of α-substituted amino acids | ZOECON CORPORATION (US) | 1980-10-07 | — | — | US | disclosed |