Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.61 |
| ▸ | MAOA | P21397 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | GLA | P06280 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | AR | P10275 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | CASP3 | P42574 | 2/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9265361 | 0.96 | MAOB (0.65) | MAOBMAOARAB9AKMT2AMEN1 | |
| SCHEMBL9270032 | 0.91 | MAOB (0.67) | MAOBMAOARAB9AKMT2AMEN1 | |
| SCHEMBL9192112 | 0.83 | MAOB (0.62) | MAOBMAOARAB9AKMT2AMEN1 | |
| SCHEMBL9263422 | 0.81 | HSD17B3 (0.55) | MAOBMAOAKMT2AMEN1KDM4E | |
| SCHEMBL19000918 | 0.80 | KDM4E (0.68) | MAOBMAOARAB9AKMT2AMEN1 | |
| SCHEMBL9269043 | 0.79 | AGER (0.64) | MAOBAR | |
| SCHEMBL9261233 | 0.79 | MAOB (0.58) | MAOBMAOARAB9AKMT2AMEN1 | |
| SCHEMBL10063475 | 0.79 | MAOB (0.74) | MAOBMAOARAB9AKMT2AMEN1 | |
| SCHEMBL9464272 | 0.79 | MAOB (0.70) | MAOBMAOARAB9AKMT2AMEN1 | |
| SCHEMBL18249863 | 0.78 | ALDH1A1 (0.67) | MAOBMAOARAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670833-A1 | NITROXY COMPOUNDS WITH PHARMACEUTICAL PROPERTIES | IOVIS BIOMEDICAL AND PHARMACEUTICAL CONSULTANTS (NL) | 1995-09-13 | — | — | EP | claimed |
| WO-1994012488-A1 | NITROXY COMPOUNDS WITH PHARMACEUTICAL PROPERTIES | BYK NEDERLAND BV (NL) | 1994-06-09 | — | — | WO | claimed |