Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9270967 | 1.00 | EPHX1 (0.36) | EPHX1ALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL9270471 | 0.83 | MEN1 (0.43) | EPHX1ALDH1A1LMNAGAAMEN1 | |
| SCHEMBL9273248 | 0.81 | EPHX1 (0.42) | EPHX1ALDH1A1DCUN1D1LMNAKCNK3 | |
| SCHEMBL9273251 | 0.81 | EPHX1 (0.42) | EPHX1ALDH1A1DCUN1D1LMNAKCNK3 | |
| SCHEMBL9269480 | 0.76 | CYP3A4 (0.44) | EPHX1ALDH1A1DCUN1D1LMNAKCNK3 | |
| SCHEMBL9269474 | 0.76 | CYP3A4 (0.44) | EPHX1ALDH1A1DCUN1D1LMNAKCNK3 | |
| SCHEMBL9269097 | 0.73 | DCUN1D1 (0.48) | EPHX1DCUN1D1 | |
| SCHEMBL9266428 | 0.73 | NPSR1 (0.43) | EPHX1ALDH1A1LMNANPSR1ALOX12 | |
| SCHEMBL9266431 | 0.73 | NPSR1 (0.43) | EPHX1ALDH1A1LMNANPSR1ALOX12 | |
| SCHEMBL9273330 | 0.72 | CYP3A4 (0.41) | EPHX1ALDH1A1DCUN1D1LMNAKCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420164-A | Enzyme inhibitors | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-05-30 | — | — | US | disclosed |