Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9273251 | 1.00 | EPHX1 (0.42) | EPHX1LMNAKCNK3ALDH1A1MEN1 | |
| SCHEMBL9270471 | 0.85 | MEN1 (0.43) | EPHX1LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL9269480 | 0.84 | CYP3A4 (0.44) | EPHX1LMNAKCNK3ALDH1A1CYP3A4 | |
| SCHEMBL9269474 | 0.84 | CYP3A4 (0.44) | EPHX1LMNAKCNK3ALDH1A1CYP3A4 | |
| SCHEMBL9270967 | 0.81 | EPHX1 (0.36) | EPHX1LMNAKCNK3ALDH1A1MEN1 | |
| SCHEMBL9270970 | 0.81 | EPHX1 (0.36) | EPHX1LMNAKCNK3ALDH1A1MEN1 | |
| SCHEMBL9273330 | 0.81 | CYP3A4 (0.41) | EPHX1LMNAKCNK3ALDH1A1MEN1 | |
| SCHEMBL9273333 | 0.81 | CYP3A4 (0.41) | EPHX1LMNAKCNK3ALDH1A1MEN1 | |
| SCHEMBL9269097 | 0.79 | DCUN1D1 (0.48) | EPHX1DCUN1D1 | |
| SCHEMBL9266431 | 0.77 | NPSR1 (0.43) | EPHX1LMNAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420164-A | Enzyme inhibitors | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-05-30 | — | — | US | disclosed |