Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 9/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 8/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9429629 | 1.00 | ABCC9 (0.51) | ABCC9ABCB1SIRT2CYP3A4ALOX15 | |
| SCHEMBL9429622 | 1.00 | ABCC9 (0.51) | ABCC9ABCB1SIRT2CYP3A4ALOX15 | |
| SCHEMBL9691273 | 0.91 | ABCC9 (0.49) | ABCC9ABCB1CYP3A4ALOX15 | |
| SCHEMBL8615119 | 0.88 | ABCB1 (0.53) | ABCC9ABCB1CYP3A4ALOX15 | |
| SCHEMBL8612374 | 0.88 | ABCB1 (0.53) | ABCC9ABCB1CYP3A4ALOX15 | |
| SCHEMBL8611166 | 0.88 | ABCB1 (0.53) | ABCC9ABCB1CYP3A4ALOX15 | |
| SCHEMBL9272734 | 0.87 | ABCC9 (0.67) | ABCC9ABCB1 | |
| SCHEMBL9272726 | 0.87 | ABCC9 (0.67) | ABCC9ABCB1 | |
| SCHEMBL9267688 | 0.87 | ABCC9 (0.67) | ABCC9ABCB1 | |
| SCHEMBL9267679 | 0.87 | ABCC9 (0.67) | ABCC9ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462761-A2 | Benzopyran derivatives and heterocyclic analogs thereof as antiischemic agents | E.R. SQUIBB & SONS, INC. (US) | 1991-12-27 | — | — | EP | claimed |
| US-5466817-A | Benzopyran derivatives and heterocyclic analogs thereof as antiischemic agents | E.R. SQUIBB & SONS, INC. (US) | 1995-11-14 | — | — | US | disclosed |
| US-5276168-A | Benzopyran derivatives and heterocyclic analogs thereof as antiischemic agents | E. R. SQUIBB & SONS, INC. (US) | 1994-01-04 | — | — | US | disclosed |
| EP-0462761-A2 | Benzopyran derivatives and heterocyclic analogs thereof as antiischemic agents | E.R. SQUIBB & SONS, INC. (US) | 1991-12-27 | — | — | EP | disclosed |