SCHEMBL9272010

SCHEMBL9272010

CCCCC[Si]1(c2ccccc2)CCC(C=O)CC1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
KCNH2 Q12809 2/20 0.32
SIGMAR1 Q99720 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8837052 0.90
SCHEMBL7759928 0.83 KCNH2 (0.32) LMNATDP1KCNH2MEN1KMT2A
SCHEMBL8984996 0.82
SCHEMBL7758795 0.80 TSHR (0.33) LMNAKCNH2
SCHEMBL8073703 0.80 KCNH2 (0.39) KCNH2
SCHEMBL8837098 0.80 SLC6A2 (0.31)
SCHEMBL8073707 0.79 KCNH2 (0.41) KCNH2
SCHEMBL7760259 0.78 KCNH2 (0.34) KCNH2
SCHEMBL8003567 0.78 KCNH2 (0.34) KCNH2SIGMAR1
SCHEMBL7755593 0.78 KCNH2 (0.32) KCNH2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7304780-A None JP disclosed
JP-H07304780-A SILACYCLOHEXANECARBALDEHYDE COMPOUND AND PRODUCTION OF SILACYCLOHEXANE-TYPE LIQUID CRYSTAL COMPOUND USING THE SAME SHIN ETSU CHEM CO LTD 1995-11-21 JP disclosed