Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9273631 | 1.00 | MAPT (0.52) | MAPTALDH1A1CYP11B1CYP11B2KMT2A | |
| SCHEMBL12782094 | 0.87 | ALDH1A1 (0.51) | MAPTALDH1A1CYP11B1CYP11B2KMT2A | |
| SCHEMBL21247872 | 0.85 | ALDH1A1 (0.67) | MAPTALDH1A1KMT2AMEN1CRHBP | |
| SCHEMBL9264299 | 0.83 | L3MBTL1 (0.56) | MAPTALDH1A1KMT2AMEN1CRHBP | |
| SCHEMBL16398787 | 0.83 | GAA (0.50) | ALDH1A1RAB9ANPSR1NAMPTNPC1 | |
| SCHEMBL29182467 | 0.83 | ALDH1A1 (0.57) | MAPTALDH1A1KMT2AMEN1CRHBP | |
| SCHEMBL4517966 | 0.79 | L3MBTL1 (0.51) | MAPTALDH1A1KMT2AMEN1CRHBP | |
| SCHEMBL25214800 | 0.77 | ALDH1A1 (0.41) | MAPTALDH1A1KMT2AMEN1CRHBP | |
| SCHEMBL11856687 | 0.77 | GAA (0.53) | MAPTALDH1A1KMT2AMEN1CRHBP | |
| SCHEMBL7370263 | 0.75 | TRPV1 (0.57) | MAPTALDH1A1CYP11B1CYP11B2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5466817-A | Benzopyran derivatives and heterocyclic analogs thereof as antiischemic agents | E.R. SQUIBB & SONS, INC. (US) | 1995-11-14 | — | — | US | disclosed |