Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.55 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.55 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024785 | 0.91 | AGTR1 (0.65) | AGTR1AGTR2TLR8 | |
| SCHEMBL9025617 | 0.83 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL9024072 | 0.82 | AGTR1 (0.70) | AGTR1AGTR2 | |
| SCHEMBL9025200 | 0.80 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL9271984 | 0.80 | AGTR1 (0.52) | AGTR1AGTR2 | |
| Hydrochloric Acid SCHEMBL8992382 | 0.79 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL9273712 | 0.79 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL9844226 | 0.78 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL8088458 | 0.77 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL8792974 | 0.77 | AGTR2 (0.70) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0654030-A1 | IMIDAZOLE DERIVATIVES HAVING A II ANTAGONIST ACTIVITY. | LUSO FARMACO INST (IT) | 1995-05-24 | — | — | EP | disclosed |