Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27533433 | 1.00 | THRB (0.55) | THRBCYP2C9ATMALDH1A1LMNA | |
| SCHEMBL9274202 | 1.00 | THRB (0.55) | THRBCYP2C9ATMALDH1A1LMNA | |
| SCHEMBL2307504 | 0.92 | THRB (0.44) | THRBCYP2C9ALDH1A1LMNAHTT | |
| SCHEMBL9274200 | 0.92 | THRB (0.44) | THRBCYP2C9ALDH1A1LMNAHTT | |
| SCHEMBL7536676 | 0.92 | THRB (0.44) | THRBCYP2C9ALDH1A1LMNAHTT | |
| SCHEMBL1615681 | 0.82 | NAAA (0.40) | THRBCYP2C9ALDH1A1LMNAHTT | |
| SCHEMBL1337905 | 0.81 | NPSR1 (0.42) | THRBCYP2C9ALDH1A1LMNAHTT | |
| SCHEMBL1337900 | 0.81 | NPSR1 (0.42) | THRBCYP2C9ALDH1A1LMNAHTT | |
| SCHEMBL4953808 | 0.79 | THRB (0.49) | THRBCYP2C9ATMALDH1A1LMNA | |
| SCHEMBL4953828 | 0.79 | THRB (0.49) | THRBCYP2C9ATMALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687252-A1 | 2-PHENOXYETHYLAMINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTICAL USE | PIERRE FABRE MEDICAMENT (FR) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020466-A1 | NOVEL 2-PHENOXY ETHYLAMINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTICAL USE | PIERRE FABRE MEDICAMENT (FR) | 1994-09-15 | — | — | WO | disclosed |