Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CETP | P11597 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | UBE2N | P61088 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9215074 | 0.92 | LMNA (0.59) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL27994192 | 0.92 | LMNA (0.56) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL27904140 | 0.90 | LMNA (0.54) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL22122578 | 0.90 | LMNA (0.74) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL3627525 | 0.90 | LMNA (0.74) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL341791 | 0.90 | LMNA (0.60) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL730670 | 0.88 | LMNA (0.55) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL906616 | 0.88 | LMNA (0.71) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL27881032 | 0.88 | LMNA (0.71) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL1164933 | 0.86 | LMNA (0.59) | LMNACYP2D6SPHK1GMNNPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0216624-B1 | Pesticidal compounds | ROUSSEL UCLAF (FR) | 1995-02-22 | — | — | EP | disclosed |