Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 7/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.50 |
| ▸ | CNR2 | P34972 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CNR1 | P21554 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | PPARD | Q03181 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28248969 | 0.90 | GABRA1 (0.53) | GABRA1GABRB2CNR2MAPTMEN1 | |
| SCHEMBL7198375 | 0.86 | GABRA1 (0.41) | GABRA1GABRB2CNR2MAPTMEN1 | |
| SCHEMBL4620939 | 0.86 | GABRA1 (0.41) | GABRA1GABRB2CNR2MAPTMEN1 | |
| SCHEMBL7194022 | 0.83 | PTGDR2 (0.43) | GABRA1GABRB2CNR2MAPTMEN1 | |
| SCHEMBL1533221 | 0.82 | TAAR1 (0.50) | GABRA1GABRB2CNR2MAPTMEN1 | |
| SCHEMBL333171 | 0.81 | GABRA1 (0.73) | GABRA1GABRB2CNR2MAPTMEN1 | |
| SCHEMBL27559267 | 0.81 | GABRA1 (0.44) | GABRA1GABRB2CNR2MAPTMEN1 | |
| SCHEMBL2548493 | 0.81 | MEN1 (0.44) | GABRA1GABRB2CNR2MAPTMEN1 | |
| SCHEMBL6547005 | 0.81 | GABRA1 (0.49) | GABRA1GABRB2CNR2MAPTMEN1 | |
| SCHEMBL19031680 | 0.80 | P2RY6 (0.38) | GABRA1GABRB2CNR2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440593-B1 | Oxidation of tertiary-alkyl substituted aromatics and catalysts therefor | MONSANTO CO (US) | 1995-07-19 | — | — | EP | claimed |
| US-5068407-A | OXIDATION OF TERTIARY-ALKYL SUBSTITUTED AROMATICS | MONSANTO COMPANY (US) | 1991-11-26 | — | — | US | claimed |