Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9266884 | 0.81 | EPHX2 (0.54) | KMT2AEPHX1EPHX2ALDH1A1 | |
| SCHEMBL9272996 | 0.80 | KMT2A (0.53) | KMT2ATP53EPHX1 | |
| SCHEMBL9274428 | 0.79 | KMT2A (0.62) | KMT2AEPHX1SMN1; SMN2EPHX2RAB9A | |
| SCHEMBL19628960 | 0.77 | KCNA3 (0.55) | KMT2AEPHX2OPRM1OPRL1RAB9A | |
| SCHEMBL9273456 | 0.76 | KMT2A (0.49) | KMT2ATP53EPHX1SMN1; SMN2EPHX2 | |
| SCHEMBL9640303 | 0.74 | CNR1 (0.58) | KMT2ATP53CACNA1CSCN5ASMN1; SMN2 | |
| SCHEMBL9641008 | 0.73 | CACNA1C (0.47) | CACNA1CSCN5AMAPTNPSR1KDM4E | |
| SCHEMBL9641210 | 0.73 | CACNA1C (0.47) | CACNA1CSCN5AMAPTNPSR1KDM4E | |
| SCHEMBL9641110 | 0.72 | LMNA (0.57) | KMT2ATP53SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL9270478 | 0.71 | EPHX2 (0.69) | KMT2AEPHX2RAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420164-A | Enzyme inhibitors | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0507291-A1 | Cyclohexylurea compounds | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |