Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | UBE2M | P61081 | 1/20 | 0.45 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2750677 | 0.79 | KMT2A (0.97) | KMT2AEPHX2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9274499 | 0.79 | KMT2A (0.51) | KMT2AEPHX2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9270646 | 0.77 | RAB9A (0.67) | KMT2AEPHX2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9275859 | 0.75 | RAB9A (0.62) | KMT2AEPHX2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9270866 | 0.75 | NPC1 (0.62) | KMT2AEPHX2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9273027 | 0.75 | EPHX2 (0.51) | EPHX2RAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL9271582 | 0.75 | MAPT (0.58) | KMT2ATSHRMEN1TAS1R3TAS1R1 | |
| SCHEMBL9271464 | 0.74 | NPC1 (0.59) | KMT2AEPHX2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9273198 | 0.73 | NPC1 (0.65) | KMT2AEPHX2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL18658002 | 0.72 | CCR3 (0.78) | KMT2ASMN1; SMN2TSHRDCUN1D1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420164-A | Enzyme inhibitors | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0507291-A1 | Cyclohexylurea compounds | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |