Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.73 |
| ▸ | MAOB | P27338 | 4/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.58 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.58 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 5/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | KDM4A | O75164 | 2/20 | 0.54 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15966133 | 1.00 | SIGMAR1 (0.73) | SIGMAR1MAOBMAOACARM1PRMT6 | |
| SCHEMBL15966143 | 1.00 | SIGMAR1 (0.73) | SIGMAR1MAOBMAOACARM1PRMT6 | |
| SCHEMBL9274175 | 1.00 | SIGMAR1 (0.73) | SIGMAR1MAOBMAOACARM1PRMT6 | |
| SCHEMBL7190739 | 1.00 | SIGMAR1 (0.73) | SIGMAR1MAOBMAOACARM1PRMT6 | |
| SCHEMBL278595 | 1.00 | SIGMAR1 (0.73) | SIGMAR1MAOBMAOACARM1PRMT6 | |
| SCHEMBL9717415 | 1.00 | SIGMAR1 (0.73) | SIGMAR1MAOBMAOACARM1PRMT6 | |
| SCHEMBL9131293 | 1.00 | SIGMAR1 (0.73) | SIGMAR1MAOBMAOACARM1PRMT6 | |
| SCHEMBL10352566 | 1.00 | SIGMAR1 (0.73) | SIGMAR1MAOBMAOACARM1PRMT6 | |
| SCHEMBL2326491 | 1.00 | SIGMAR1 (0.73) | SIGMAR1MAOBMAOACARM1PRMT6 | |
| SCHEMBL11040881 | 1.00 | SIGMAR1 (0.73) | SIGMAR1MAOBMAOACARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2646008-A1 | TRANSDERMAL THERAPEUTIC SYSTEM (TTS) COMPRISING ROTIGOTINE | Ratiopharm GmbH (DE) | 2013-10-09 | — | — | EP | disclosed |
| WO-2012072650-A1 | TRANSDERMAL THERAPEUTIC SYSTEM (TTS) COMPRISING ROTIGOTINE | RATIOPHARM GMBH (DE) | 2012-06-07 | — | — | WO | disclosed |