SCHEMBL6366898

SCHEMBL6366898

CCCCCCCCN(C)Cc1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ SIGMAR1 Q99720 4/20 0.73
▸ MAOB P27338 4/20 0.59
▸ MAOA P21397 1/20 0.59
▸ CARM1 Q86X55 1/20 0.58
▸ PRMT6 Q96LA8 1/20 0.58
▸ PRMT8 Q9NR22 1/20 0.58
▸ ACHE P22303 5/20 0.56
▸ KCNH2 Q12809 1/20 0.54
▸ KDM4A O75164 2/20 0.54
▸ KDM4C Q9H3R0 2/20 0.54
▸ LMNA P02545 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL278595 1.00 SIGMAR1 (0.73) SIGMAR1MAOBMAOACARM1PRMT6
SCHEMBL9275367 1.00 SIGMAR1 (0.73) SIGMAR1MAOBMAOACARM1PRMT6
SCHEMBL9131293 1.00 SIGMAR1 (0.73) SIGMAR1MAOBMAOACARM1PRMT6
SCHEMBL10773804 1.00 SIGMAR1 (0.73) SIGMAR1MAOBMAOACARM1PRMT6
SCHEMBL9274175 1.00 SIGMAR1 (0.73) SIGMAR1MAOBMAOACARM1PRMT6
SCHEMBL11040881 1.00 SIGMAR1 (0.73) SIGMAR1MAOBMAOACARM1PRMT6
SCHEMBL15966143 1.00 SIGMAR1 (0.73) SIGMAR1MAOBMAOACARM1PRMT6
SCHEMBL15966133 1.00 SIGMAR1 (0.73) SIGMAR1MAOBMAOACARM1PRMT6
SCHEMBL3805871 1.00 SIGMAR1 (0.73) SIGMAR1MAOBMAOACARM1PRMT6
SCHEMBL10352566 1.00 SIGMAR1 (0.73) SIGMAR1MAOBMAOACARM1PRMT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4155872-A AMINE SALTS OF CARBOXYLIC ACID, INCREASED TURBIDITY AND RESPONSE SPEED SHARP CORPORATION (JP) 1979-05-22 — — US claimed
US-9840680-B2 Fragrance compositions comprising ionic liquids THE PROCTER & GAMBLE COMPANY (US) 2017-12-12 — — US disclosed
US-20160151527-A1 Ionic Liquids THE PROCTER & GAMBLE COMPANY 2016-06-02 — — US disclosed
US-20160115424-A1 FRAGRANCE COMPOSITIONS COMPRISING IONIC LIQUIDS THE PROCTER & GAMBLE COMPANY 2016-04-28 — — US disclosed
WO-2016049391-A1 IONIC LIQUIDS THE PROCTER & GAMBLE COMPANY (US) 2016-03-31 — — WO disclosed
WO-2016049390-A1 FRAGRANCE COMPOSITIONS COMPRISING IONIC LIQUIDS THE PROCTER & GAMBLE COMPANY (US) 2016-03-31 — — WO disclosed
CN-103958016-B Neutral Zwitterionic Displacer Molecules for Hydrophobic Displacement Chromatography SACHEM, INC. (US) 2015-12-23 — — CN disclosed
US-9120846-B2 Neutral zwitterionic displacer molecules for hydrophobic displacement chromatography SACHEM, INC. (US) 2015-09-01 — — US disclosed
US-20140256910-A1 NEUTRAL ZWITTERIONIC DISPLACER MOLECULES FOR HYDROPHOBIC DISPLACEMENT CHROMATOGRAPHY PNC BANK, NATIONAL ASSOCIATION 2014-09-11 — — US disclosed
EP-2763774-A1 NEUTRAL ZWITTERIONIC DISPLACER MOLECULES FOR HYDROPHOBIC DISPLACEMENT CHROMATOGRAPHY Sachem, Inc. (US) 2014-08-13 — — EP disclosed
CN-103958016-A Neutral zwitterionic displacer molecules for hydrophobic displacement chromatography SACHEM INC 2014-07-30 — — CN disclosed
WO-2013052087-A1 NEUTRAL ZWITTERIONIC DISPLACER MOLECULES FOR HYDROPHOBIC DISPLACEMENT CHROMATOGRAPHY SACHEM, INC. (US) 2013-04-11 — — WO disclosed
EP-2165829-A1 Lithographic printing plate precursor and plate making method thereof Fujifilm Corporation (JP) 2010-03-24 — — EP disclosed
US-20050245422-A1 Alkali cleaner SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2005-11-03 — — US disclosed
US-4155872-A AMINE SALTS OF CARBOXYLIC ACID, INCREASED TURBIDITY AND RESPONSE SPEED SHARP CORPORATION (JP) 1979-05-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140256910-A1 NEUTRAL ZWITTERIONIC DISPLACER MOLECULES FOR HYDROPHOBIC DISPLACEMENT CHROMATOGRAPHY SLCO4C1, SLCO2A1, SLCO2B1 SIGMAR1 32/4885MAOB 4085/4885MAOA 3724/4885
US-20160115424-A1 FRAGRANCE COMPOSITIONS COMPRISING IONIC LIQUIDS CUTA, TRPA1, POLR1C SIGMAR1 1911/4885MAOB 1932/4885MAOA 1013/4885
US-20160151527-A1 Ionic Liquids SLC6A6, SLC6A9, PIP4K2C SIGMAR1 3120/4885MAOB 4706/4885MAOA 4729/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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