SCHEMBL9275385

SCHEMBL9275385

CCCCCC(C(N)=O)c1nc2ccccc2[nH]1

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.58
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
SPHK2 Q9NRA0 1/20 0.48
SPHK1 Q9NYA1 1/20 0.48
KMT2A Q03164 1/20 0.47
IDO1 P14902 1/20 0.47
TAAR1 Q96RJ0 1/20 0.46
DAGLA Q9Y4D2 1/20 0.46
ALOX12 P18054 1/20 0.44
POLB P06746 1/20 0.43
FPR1 P21462 1/20 0.43
BCHE P06276 1/20 0.43
TRPC3 Q13507 1/20 0.43
TRPC4 Q9UBN4 1/20 0.43
TRPC5 Q9UL62 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28420241 0.87 ALDH1A1 (0.58) ALDH1A1NPC1RAB9ASMN1; SMN2SPHK2
SCHEMBL28416316 0.87 ALDH1A1 (0.58) ALDH1A1NPC1RAB9ASMN1; SMN2SPHK2
SCHEMBL28421573 0.87 ALDH1A1 (0.58) ALDH1A1NPC1RAB9ASMN1; SMN2SPHK2
SCHEMBL28419559 0.87 ALDH1A1 (0.58) ALDH1A1NPC1RAB9ASMN1; SMN2SPHK2
SCHEMBL28415424 0.87 ALDH1A1 (0.58) ALDH1A1NPC1RAB9ASMN1; SMN2SPHK2
SCHEMBL27864714 0.81 ALDH1A1 (0.59) ALDH1A1NPC1RAB9ASMN1; SMN2SPHK2
SCHEMBL7433448 0.79 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2KMT2AIDO1TAAR1
SCHEMBL668255 0.79 ALDH1A1 (0.57) ALDH1A1NPC1RAB9ASMN1; SMN2SPHK2
SCHEMBL7854778 0.78 ALDH1A1 (0.55) ALDH1A1NPC1RAB9ASMN1; SMN2SPHK2
SCHEMBL2679996 0.78 ALDH1A1 (0.55) ALDH1A1NPC1RAB9ASMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5493011-A PIGMENTING HIGH MOLECULAR WEIGHT NATURAL OR SYNTHETIC ORGANIC MATERIALS HOECHST AG (DE) 1996-02-20 US disclosed
US-5493011-A PIGMENTING HIGH MOLECULAR WEIGHT NATURAL OR SYNTHETIC ORGANIC MATERIALS HOECHST AG (DE) 1996-02-20 US disclosed