Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 9/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | NPY4R | P50391 | 8/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.37 |
| ▸ | NPY2R | P49146 | 3/20 | 0.37 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.37 |
| ▸ | CHRNG | P07510 | 2/20 | 0.37 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.37 |
| ▸ | CHRND | Q07001 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.35 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8119413 | 0.89 | NPY1R (0.38) | TRPV1NPY1RCCR5NPY4RNPY5R | |
| SCHEMBL9276185 | 0.87 | CNR1 (0.40) | TRPV1CNR1CNR2TPSAB1 | |
| SCHEMBL9201861 | 0.83 | TRPV1 (0.41) | TRPV1NPY1RNPY4RNPY5RNPY2R | |
| SCHEMBL8112716 | 0.82 | CNR1 (0.37) | CNR1 | |
| SCHEMBL4650760 | 0.79 | TRPV1 (0.41) | TRPV1NPY1RNPY4RNPY5RNPY2R | |
| SCHEMBL8125897 | 0.78 | HDAC1 (0.45) | CCR5CNR1CNR2 | |
| SCHEMBL9195693 | 0.78 | NPY1R (0.42) | NPY1RNPY4RNPY5RNPY2RCNR1 | |
| SCHEMBL8114448 | 0.78 | NPY1R (0.39) | TRPV1NPY1RCCR5NPY4RNPY5R | |
| SCHEMBL4652029 | 0.78 | TRPV1 (0.45) | TRPV1CHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL9201144 | 0.77 | NPY1R (0.42) | TRPV1NPY1RNPY4RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |