Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 9/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 3/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.34 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.33 |
| ▸ | CHRNG | P07510 | 1/20 | 0.33 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.33 |
| ▸ | CHRND | Q07001 | 1/20 | 0.33 |
| ▸ | NPY4R | P50391 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8121876 | 0.94 | F2 (0.37) | NPY1RF2CCR5MAPTHTT | |
| SCHEMBL8122123 | 0.90 | HDAC1 (0.42) | F2CCR5 | |
| SCHEMBL8123419 | 0.85 | TRPV1 (0.37) | NPY1RF2TRPV1NPY5RNPY2R | |
| SCHEMBL8125989 | 0.83 | NPY1R (0.37) | NPY1RF2TRPV1NPY5RNPY2R | |
| Hydrochloric Acid SCHEMBL8119516 | 0.81 | NPY1R (0.39) | NPY1RF2NPY5RNPFFR1NPFFR2 | |
| SCHEMBL8124247 | 0.81 | NPY1R (0.42) | NPY1RF2NPY5RNPFFR1NPFFR2 | |
| SCHEMBL8128053 | 0.80 | F2 (0.42) | NPY1RF2 | |
| SCHEMBL8114061 | 0.78 | PLAAT3 (0.41) | NPY1RF2TRPV1NPY5RNPY2R | |
| SCHEMBL8121919 | 0.78 | NPY1R (0.35) | NPY1RF2NPY5RNPY2RNPY4R | |
| SCHEMBL9275992 | 0.78 | TRPV1 (0.39) | NPY1RTRPV1CCR5NPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |