Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9102734 | 0.85 | USP2 (0.48) | USP2ALOX15OPRD1OPRM1TSHR | |
| SCHEMBL9102724 | 0.85 | USP2 (0.48) | USP2ALOX15OPRD1OPRM1TSHR | |
| SCHEMBL9280325 | 0.85 | USP2 (0.50) | USP2ALOX15TSHRNTSR1MCHR1 | |
| SCHEMBL9104918 | 0.82 | USP2 (0.51) | USP2ALOX15OPRD1TSHRNTSR1 | |
| SCHEMBL9104927 | 0.82 | USP2 (0.51) | USP2ALOX15OPRD1TSHRNTSR1 | |
| SCHEMBL9104500 | 0.75 | USP2 (0.51) | USP2ALOX15OPRD1TSHRNTSR1 | |
| SCHEMBL9104181 | 0.74 | USP2 (0.50) | USP2ALOX15TSHRMCHR1 | |
| SCHEMBL9104187 | 0.74 | USP2 (0.50) | USP2ALOX15TSHRMCHR1 | |
| SCHEMBL9274530 | 0.73 | HRH3 (0.44) | USP2ALOX15TSHRCHRM2CYP2D6 | |
| SCHEMBL9103203 | 0.72 | SLC6A4 (0.46) | USP2ALOX15OPRD1OPRM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012074469-A1 | NEW IKACH BLOCKERS | ASTRAZENECA AB (SE) | 2012-06-07 | — | — | WO | disclosed |