Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9274530 | 0.88 | HRH3 (0.44) | USP2ALOX15TSHRCHRM2SIGMAR1 | |
| SCHEMBL9277892 | 0.87 | ALDH1A1 (0.43) | NTSR1CHRM2ADRA2BDRD3SIGMAR1 | |
| SCHEMBL9274754 | 0.86 | SLC6A4 (0.41) | USP2ALOX15 | |
| SCHEMBL9276014 | 0.85 | USP2 (0.48) | USP2ALOX15MCHR1TSHRNTSR1 | |
| SCHEMBL9275071 | 0.85 | HRH3 (0.41) | USP2ALOX15MCHR1TSHRNTSR1 | |
| SCHEMBL9104187 | 0.84 | USP2 (0.50) | USP2ALOX15MCHR1TSHR | |
| SCHEMBL9104181 | 0.84 | USP2 (0.50) | USP2ALOX15MCHR1TSHR | |
| SCHEMBL9278651 | 0.84 | P2RX7 (0.38) | USP2ALOX15MCHR1TSHRNTSR1 | |
| SCHEMBL9280185 | 0.84 | P2RX7 (0.38) | USP2ALOX15MCHR1TSHRNTSR1 | |
| SCHEMBL9280179 | 0.83 | HDAC4 (0.38) | USP2ALOX15MCHR1TSHRADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012074469-A1 | NEW IKACH BLOCKERS | ASTRAZENECA AB (SE) | 2012-06-07 | — | — | WO | disclosed |