Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TACR2 | P21452 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9275071 | 0.88 | HRH3 (0.41) | HRH3CHRM2CHRM3CYP2D6USP2 | |
| SCHEMBL9280325 | 0.88 | USP2 (0.50) | HRH3CHRM2USP2ALOX15TSHR | |
| SCHEMBL9104340 | 0.86 | HRH3 (0.44) | HRH3CHRM2CHRM3CYP2D6USP2 | |
| SCHEMBL9104334 | 0.86 | HRH3 (0.44) | HRH3CHRM2CHRM3CYP2D6USP2 | |
| SCHEMBL9279426 | 0.83 | HRH3 (0.39) | HRH3SIGMAR1OPRK1 | |
| SCHEMBL9280185 | 0.82 | P2RX7 (0.38) | CHRM2CHRM3USP2ALOX15TSHR | |
| SCHEMBL9102627 | 0.81 | HRH3 (0.43) | HRH3CHRM2CHRM3CYP2D6TACR2 | |
| SCHEMBL9102635 | 0.81 | HRH3 (0.43) | HRH3CHRM2CHRM3CYP2D6TACR2 | |
| SCHEMBL9281360 | 0.80 | HRH3 (0.45) | HRH3CHRM2CHRM3TSHRTACR2 | |
| SCHEMBL9278651 | 0.80 | P2RX7 (0.38) | USP2ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012074469-A1 | NEW IKACH BLOCKERS | ASTRAZENECA AB (SE) | 2012-06-07 | — | — | WO | disclosed |