Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9216687 | 0.90 | ALDH1A1 (0.39) | MAPTGAAALDH1A1KDM4ENPC1 | |
| SCHEMBL9267498 | 0.86 | GAA (0.53) | MAPTGAATP53NLRP3 | |
| SCHEMBL9701450 | 0.85 | ALDH1A1 (0.40) | MAPTGAAALDH1A1KDM4ENPC1 | |
| SCHEMBL7458450 | 0.84 | ALOX15 (0.41) | GAAALDH1A1NPC1SMN1; SMN2TP53 | |
| SCHEMBL7452294 | 0.84 | GAA (0.47) | MAPTGAASMN1; SMN2TP53NLRP3 | |
| SCHEMBL7455217 | 0.83 | GAA (0.47) | MAPTGAAALDH1A1KDM4ENPC1 | |
| SCHEMBL11003825 | 0.81 | ALDH1A1 (0.46) | MAPTGAAALDH1A1KDM4ENPC1 | |
| SCHEMBL10507458 | 0.79 | GAA (0.39) | MAPTGAAALDH1A1KDM4ENPC1 | |
| SCHEMBL10505644 | 0.79 | GAA (0.40) | MAPTGAAALDH1A1KDM4ENPC1 | |
| SCHEMBL10845099 | 0.79 | ALDH1A1 (0.43) | MAPTGAAALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639190-A1 | PYRIDINE SULFONYL UREA DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-02-22 | — | — | EP | claimed |
| WO-1992014728-A1 | PYRIDINE SULFONYL UREA DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-09-03 | — | — | WO | claimed |