Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 4/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 3/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9279141 | 0.89 | AKR1C4 (0.44) | MAPTGAAALDH1A1CASP1PTPN1 | |
| SCHEMBL9276254 | 0.84 | MAPT (0.35) | MAPTGAADPP4ALDH1A1TSHR | |
| SCHEMBL2408682 | 0.84 | DPP4 (0.52) | MAPTGAADPP4ALDH1A1TSHR | |
| SCHEMBL29941102 | 0.84 | DPP4 (0.52) | MAPTGAADPP4ALDH1A1TSHR | |
| SCHEMBL9279280 | 0.78 | AKR1C2 (0.38) | MAPTGAAALDH1A1TSHRCASP1 | |
| SCHEMBL9274280 | 0.76 | AKR1C2 (0.47) | MAPTGAAALDH1A1TSHRTP53 | |
| Hydrochloric Acid SCHEMBL9194113 | 0.74 | AKR1C2 (0.46) | MAPTGAAALDH1A1TSHRTP53 | |
| SCHEMBL2962331 | 0.73 | CASP7 (0.48) | MAPTGAAALDH1A1TSHRCASP1 | |
| SCHEMBL9273928 | 0.72 | AKR1C4 (0.47) | MAPTGAAALDH1A1CASP1PTPN1 | |
| SCHEMBL7778450 | 0.72 | ALDH1A1 (0.44) | MAPTGAADPP4ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643686-A1 | NEW COMPOUNDS | Astra Aktiebolag (SE) | 1995-03-22 | — | — | EP | disclosed |