Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | CHKA | P35790 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8375674 | 0.91 | RARB (0.50) | APPRARBPSEN1PSEN2APH1B | |
| SCHEMBL8857691 | 0.90 | RARB (0.45) | RARBGRM2CHKAMCHR1MEN1 | |
| SCHEMBL9270795 | 0.89 | APP (0.41) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8378005 | 0.89 | KMT2A (0.40) | APPRARBPSEN1PSEN2APH1B | |
| SCHEMBL17586079 | 0.87 | RARB (0.43) | RARBGRM2CHKAMCHR1MEN1 | |
| SCHEMBL8507964 | 0.87 | RARB (0.46) | RARBGRM2CHKAMCHR1MEN1 | |
| SCHEMBL9399967 | 0.81 | RARB (0.52) | RARBCHKAMAPTNPC1TP53 | |
| SCHEMBL8857743 | 0.80 | RARB (0.58) | RARBGRM2CHKACYP2C19CYP2C9 | |
| SCHEMBL9796203 | 0.80 | RARB (0.52) | APPRARBPSEN1PSEN2APH1B | |
| SCHEMBL8375685 | 0.80 | RARB (0.52) | RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657039-A1 | PAPER WHITE PDLC SYSTEM | MERCK PATENT GmbH (DE) | 1995-06-14 | — | — | EP | disclosed |
| WO-1994004958-A1 | PAPER WHITE PDLC SYSTEM | MERCK PATENT GMBH (DE) | 1994-03-03 | — | — | WO | disclosed |