SCHEMBL9277995

SCHEMBL9277995

CCOC(=S)Sc1cccc(OCc2ccccc2)c1

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.49
CYP4F2 P78329 1/20 0.47
CYP4A11 Q02928 1/20 0.47
BCHE P06276 4/20 0.46
NR4A2 P43354 1/20 0.46
LMNA P02545 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
LTB4R Q15722 1/20 0.43
LTB4R2 Q9NPC1 1/20 0.43
MAOA P21397 1/20 0.43
JAK2 O60674 1/20 0.42
JAK3 P52333 1/20 0.42
MEN1 O00255 1/20 0.42
HSP90AA1 P07900 1/20 0.42
KMT2A Q03164 1/20 0.42
SMPD1 P17405 1/20 0.42
NR1H4 Q96RI1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3440505 0.81 GABRA1 (0.38)
SCHEMBL27656494 0.78 MAOB (0.62) MAOBCYP4F2CYP4A11NR4A2LTB4R
SCHEMBL11855841 0.78 ALDH1A1 (0.41) L3MBTL1MEN1KMT2A
SCHEMBL770110 0.77 DHODH (0.41) MEN1KMT2A
SCHEMBL28961906 0.76 ALDH1A1 (0.41) LMNAL3MBTL1MEN1KMT2A
SCHEMBL165269 0.76 ALDH1A1 (0.41)
SCHEMBL11566779 0.75 MAOB (0.62) MAOBCYP4F2CYP4A11BCHENR4A2
SCHEMBL3175420 0.75 MAOB (0.61) MAOBCYP4F2CYP4A11BCHENR4A2
SCHEMBL3080494 0.75 MAOB (0.55) MAOBCYP4F2CYP4A11BCHENR4A2
SCHEMBL865387 0.73 CA12 (0.53) LMNAL3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012073249-A1 A NOVEL PROCESS FOR THE PREPARATION OF 3-(BENZYLOXY)- BENZENETHIOL, A KEY INTERMEDIATE FOR THE PREPARATION OF PHARMACEUTICAL DRUGS. ARCH PHARMALABS LIMITED (IN) 2012-06-07 WO disclosed