SCHEMBL9278264

SCHEMBL9278264

CC(C)[Hf](c1c(C2=CC=CC2)ccc2c1Cc1ccccc1-2)C(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.34
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
PGR P06401 1/20 0.33
CYP1A2 P05177 2/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
HSD17B10 Q99714 1/20 0.32
DRD2 P14416 1/20 0.31
DRD4 P21917 1/20 0.31
DRD3 P35462 1/20 0.31
SLC6A2 P23975 2/20 0.31
SLC6A4 P31645 2/20 0.31
ADRA2A P08913 1/20 0.31
MAOA P21397 1/20 0.31
HTR2C P28335 1/20 0.31
HTR2B P41595 1/20 0.31
SRD5A2 P31213 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8679488 0.83 PNMT (0.36) PNMTNPC1RAB9APGRCYP1A2
SCHEMBL9186251 0.80 PNMT (0.31) PNMTNPC1RAB9APGRCYP1A2
SCHEMBL27348144 0.79 PNMT (0.45) PNMTNPC1RAB9APGRDRD2
SCHEMBL9278339 0.78 PNMT (0.34) PNMTNPC1RAB9APGRCYP1A2
SCHEMBL28220071 0.78 PNMT (0.44) PNMTNPC1RAB9APGRDRD2
SCHEMBL28286932 0.78 PNMT (0.44) PNMTNPC1RAB9APGRDRD2
SCHEMBL7913219 0.77 PNMT (0.36) PNMTNPC1RAB9APGRCYP1A2
SCHEMBL3687435 0.77 PNMT (0.33) PNMTNPC1RAB9APGRCYP1A2
SCHEMBL6437444 0.77 PNMT (0.37) PNMTNPC1RAB9APGRCYP1A2
SCHEMBL28762096 0.77 PNMT (0.37) PNMTNPC1RAB9APGRCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0464684-B1 Syndiotactic crystalline copolymers of propylene SPHERILENE SRL (IT) 1995-06-14 EP claimed
EP-0422703-B1 CATALYST AND PROCESS FOR THE POLYMERIZATION AND COPOLYMERIZATION OF ALPHA-OLEFINS Enichem Anic S.r.l. (IT) 1993-06-30 EP claimed