Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25211139 | 1.00 | LMNA (0.65) | LMNAALDH1A1TSHRCYP2D6SPHK1 | |
| SCHEMBL2865637 | 1.00 | LMNA (0.65) | LMNAALDH1A1TSHRCYP2D6SPHK1 | |
| SCHEMBL9675098 | 1.00 | LMNA (0.65) | LMNAALDH1A1TSHRCYP2D6SPHK1 | |
| SCHEMBL11093027 | 0.98 | LMNA (0.61) | LMNAALDH1A1TSHRCYP2D6SPHK1 | |
| SCHEMBL7564848 | 0.96 | LMNA (0.59) | LMNAALDH1A1TSHRCYP2D6SPHK1 | |
| SCHEMBL5831688 | 0.92 | ALDH1A1 (0.58) | LMNAALDH1A1TSHRCYP2D6SPHK1 | |
| SCHEMBL25178065 | 0.87 | LMNA (0.50) | LMNAALDH1A1TSHRFAAHFFAR4 | |
| SCHEMBL25181795 | 0.87 | LMNA (0.50) | LMNAALDH1A1TSHRFAAHFFAR4 | |
| SCHEMBL9445614 | 0.87 | LMNA (0.50) | LMNAALDH1A1TSHRFAAHFFAR4 | |
| SCHEMBL15687620 | 0.87 | LMNA (0.50) | LMNAALDH1A1TSHRFAAHFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663918-A1 | PURE ENANTIOMERS OF PHOSPHORIC-ACID ESTERS AS PHOSPHOLIPASE-A2 INHIBITORS | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 1995-07-26 | — | — | EP | disclosed |
| WO-1994009014-A1 | PURE ENANTIOMERS OF PHOSPHORIC-ACID ESTERS AS PHOSPHOLIPASE-A2 INHIBITORS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 1994-04-28 | — | — | WO | disclosed |