Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 8/20 | 0.46 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9205175 | 0.90 | LTB4R2 (0.48) | LTB4R2BDKRB1PPARAALDH1A1ALOX12 | |
| SCHEMBL8979746 | 0.88 | LTB4R2 (0.55) | LTB4R2BDKRB1AGTR1AGTR2 | |
| SCHEMBL9200534 | 0.83 | LTB4R2 (0.42) | LTB4R2BDKRB1PPARAALDH1A1FOLH1 | |
| SCHEMBL9204918 | 0.81 | LTB4R2 (0.40) | LTB4R2PPARAALDH1A1CYP2C9CNR1 | |
| SCHEMBL8979799 | 0.79 | LTB4R2 (0.53) | LTB4R2BDKRB1AGTR1AGTR2 | |
| SCHEMBL9153918 | 0.78 | LTB4R2 (0.45) | LTB4R2BDKRB1AGTR1AGTR2 | |
| SCHEMBL8671881 | 0.77 | LTB4R2 (0.57) | LTB4R2BDKRB1AGTR1AGTR2 | |
| SCHEMBL8979895 | 0.76 | LTB4R2 (0.49) | LTB4R2BDKRB1AGTR1AGTR2 | |
| SCHEMBL9195365 | 0.73 | LTB4R2 (0.39) | LTB4R2PPARAALDH1A1ALOX12KMT2A | |
| SCHEMBL8979749 | 0.73 | LTB4R2 (0.48) | LTB4R2BDKRB1KDM4EAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641329-A1 | COMPOUNDS HAVING ANGIOTENSINE II ANTAGONISTIC ACTIVITY | ISTITUTO LUSO FARMACO D'ITALIA S.p.A. (IT) | 1995-03-08 | — | — | EP | disclosed |