Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.36 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9165801 | 0.95 | ALDH1A1 (0.41) | RXRARXRBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9277735 | 0.93 | RXRA (0.39) | RXRARXRBMAPTALDH1A1KDM4E | |
| SCHEMBL10047611 | 0.82 | KMT2A (0.47) | CYP1A2CYP2C9CYP2C19CYP3A4MAPT | |
| SCHEMBL9163960 | 0.81 | ABL1 (0.46) | RXRACYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL14466536 | 0.80 | NPC1 (0.46) | CYP1A2CYP2C9CYP3A4MAPTALDH1A1 | |
| SCHEMBL9581021 | 0.77 | ABL1 (0.50) | RXRACYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL11891632 | 0.75 | ALDH1A1 (0.54) | CYP1A2CYP2C9CYP2C19CYP3A4MAPT | |
| SCHEMBL24467788 | 0.74 | ABL1 (0.55) | RXRACYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL16158449 | 0.73 | ALDH1A1 (0.52) | CYP1A2CYP2C9CYP2C19CYP3A4MAPT | |
| SCHEMBL10065405 | 0.73 | ALDH1A1 (0.52) | CYP1A2CYP2C9CYP2C19CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314195-B1 | Electrophotographic sensitive material | MITA INDUSTRIAL CO LTD (JP) | 1995-03-22 | — | — | EP | disclosed |
| US-4877702-A | PERYLENE TYPE ELECTRIC CHARGE GENERATING SUBSTANCE AND DIAMINE DERIVATIVE AS ELECTRIC CHARGE TRANSFERRING SUBSTANCE | MITA INDUSTRIAL CO., LTD. (JP) | 1989-10-31 | — | — | US | disclosed |