SCHEMBL9280377

SCHEMBL9280377

C=CCC1(CC=C)OC(=O)c2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CFTR P13569 1/20 0.49
GOPC Q9HD26 1/20 0.49
LMNA P02545 4/20 0.44
MAPT P10636 4/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
POLB P06746 3/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
TDP1 Q9NUW8 3/20 0.44
GPR55 Q9Y2T6 2/20 0.44
ALDH1A1 P00352 1/20 0.44
ESR1 P03372 1/20 0.44
TP53 P04637 1/20 0.44
TYMS P04818 1/20 0.44
CYP3A4 P08684 1/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44
ESR2 Q92731 1/20 0.44
HSD17B10 Q99714 1/20 0.44
NPSR1 Q6W5P4 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4591907 0.79 CFTR (0.46) CFTRGOPCLMNAMAPTSMN1; SMN2
SCHEMBL9879489 0.79 CFTR (0.46) CFTRGOPCLMNAMAPTSMN1; SMN2
SCHEMBL13136410 0.76 CFTR (0.48) CFTRGOPCLMNAMAPTSMN1; SMN2
SCHEMBL6739516 0.76 SMN1; SMN2 (0.50) CFTRGOPCLMNAMAPTSMN1; SMN2
SCHEMBL29807800 0.72 CFTR (0.48) CFTRGOPCLMNAMAPTSMN1; SMN2
SCHEMBL1729415 0.72 CFTR (0.48) CFTRGOPCLMNAMAPTSMN1; SMN2
SCHEMBL2594088 0.70 PGR (0.51) LMNAMEN1KMT2AALDH1A1CYP3A4
SCHEMBL14422532 0.70 SMN1; SMN2 (0.45) CFTRGOPCLMNAMAPTSMN1; SMN2
SCHEMBL31628334 0.70 NPSR1 (0.51) CFTRGOPCLMNAMAPTSMN1; SMN2
SCHEMBL8031529 0.70 NPSR1 (0.51) CFTRGOPCLMNAMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-60228589-A None JP disclosed
JP-7206843-A None JP disclosed
CN-117545464-A Benefit agent delivery system using electric field 伊英克公司 2024-02-09 CN disclosed
CN-117320693-A Benefit agent delivery system using electroplating 伊英克公司 2023-12-29 CN disclosed
WO-2023127235-A1 TEMPERATURE INDICATING MATERIAL-CONTAINING ADHESIVE COMPOSITION AND SKIN-PATCH THERMOMETER USING SAME 株式会社MORESCO 2023-07-06 WO disclosed
EP-3338837-B1 SYRINGE FOR TYMPANIC INJECTION SATO PHARMA (JP) 2021-01-27 EP disclosed
US-20180243507-A1 SYRINGE FOR TYMPANIC INJECTION SATO PHARMACEUTICAL CO., LTD. (JP) 2018-08-30 US disclosed
EP-3338837-A1 SYRINGE FOR TYMPANIC INJECTION Sato Pharmaceutical Co., Ltd. (JP) 2018-06-27 EP disclosed
CN-101679721-A Resin composition, filling material, insulating layer and semiconductor device SUMITOMO BAKELITE CO 2010-03-24 CN disclosed
JP-H07206843-A VASODILATOR KAO CORP 1995-08-08 JP disclosed
EP-0237915-B1 CHROMOGENIC PHTHALIDES, THEIR PREPARATION AND USE BAYER AG (DE) 1992-05-13 EP disclosed
JP-S60228589-A REVERSIBLE THERMOCHROMIC MATERIAL PILOT INK CO LTD 1985-11-13 JP disclosed