Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TYMS | P04818 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9280377 | 0.79 | CFTR (0.49) | CFTRGOPCPOLBLMNAMAPT | |
| SCHEMBL4591907 | 0.77 | CFTR (0.46) | CFTRGOPCPOLBLMNAMAPT | |
| SCHEMBL11617825 | 0.75 | SMN1; SMN2 (0.45) | CFTRGOPCPOLBLMNAMAPT | |
| SCHEMBL28552047 | 0.73 | ATM (0.44) | CFTRGOPCPOLBLMNAMAPT | |
| SCHEMBL11249029 | 0.72 | CFTR (0.55) | CFTRGOPCPOLBLMNAMAPT | |
| SCHEMBL830872 | 0.71 | PGR (0.37) | POLBLMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL28709016 | 0.70 | NPSR1 (0.51) | CFTRGOPCPOLBMAPTSMN1; SMN2 | |
| SCHEMBL29807800 | 0.69 | CFTR (0.48) | CFTRGOPCPOLBLMNAMAPT | |
| SCHEMBL1729415 | 0.69 | CFTR (0.48) | CFTRGOPCPOLBLMNAMAPT | |
| SCHEMBL2594088 | 0.68 | PGR (0.51) | LMNAMEN1KMT2AALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112194388-A | Flame-retardant glass fiber and preparation method thereof | 罗静婷 | 2021-01-08 | — | — | CN | claimed |
| CN-110607579-A | Green and environment-friendly oil agent for nylon fiber weaving and preparation method thereof | 如皋市雨润纤维科技有限公司 | 2019-12-24 | — | — | CN | disclosed |
| US-5039686-A | Insecticides | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1991-08-13 | — | — | US | disclosed |
| EP-0369526-A2 | Nitromethylene compounds, their preparation and their use as pesticides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-05-23 | — | — | EP | disclosed |