SCHEMBL9280392

SCHEMBL9280392

Nc1[c]cccc1.[c]1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.36
ALOX15 P16050 1/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22106 0.89
Hydrochloric Acid SCHEMBL27912705 0.87
SCHEMBL27588603 0.87
SCHEMBL27692243 0.82
Acetamide SCHEMBL28086401 0.75 LMNA (0.35) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL28275526 0.70 TSHR (0.47) CYP3A4ALOX15CASP1SMN1; SMN2TSHR
SCHEMBL3696552 0.70
SCHEMBL5668038 0.70 CA4 (0.35) CYP3A4ALOX15SMN1; SMN2
SCHEMBL888112 0.70 TSHR (0.35) TSHR
Biphenyl SCHEMBL28269860 0.69 ALDH1A1 (0.60) CYP3A4SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995001357-A1 OPTICALLY ACTIVE 1-(4-NITROPHENYL)-4-METHYL-7,8-METHYLENEDIOXY-3,4-DIHYDRO-5H-2,3-BENZODIAZEPINE AND PROCESS FOR PREPARING SAME Gyógyszerkutató Intézet Kft. (HU) 1995-01-12 WO claimed
EP-0220435-A1 A method for preparing optically active half esters SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-05-06 EP disclosed