Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD4 | Q15561 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14733307 | 0.92 | TEAD4 (0.44) | TEAD4ALDH1A1MAPTTDP1POLB | |
| SCHEMBL12158795 | 0.89 | TEAD4 (0.56) | TEAD4ALDH1A1MAPTTDP1POLB | |
| SCHEMBL9074468 | 0.86 | TEAD4 (0.38) | TEAD4ALDH1A1MAPTTDP1POLB | |
| SCHEMBL9076164 | 0.86 | TEAD4 (0.41) | TEAD4ALDH1A1MAPTTDP1POLB | |
| SCHEMBL27773172 | 0.86 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2L3MBTL1ACHEMAPK1 | |
| SCHEMBL9075138 | 0.86 | MAOA (0.49) | TEAD4ALDH1A1MAPTTDP1POLB | |
| SCHEMBL9073407 | 0.85 | CYP19A1 (0.39) | TEAD4ALDH1A1MAPTTDP1POLB | |
| SCHEMBL9075126 | 0.84 | TEAD4 (0.36) | TEAD4ALDH1A1MAPTTDP1POLB | |
| SCHEMBL9073459 | 0.84 | TEAD4 (0.39) | TEAD4ALDH1A1MAPTTDP1POLB | |
| SCHEMBL9073223 | 0.84 | ALDH1A1 (0.51) | TEAD4ALDH1A1MAPTTDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430195-A | Diamino compounds and liquid crystal aligning films | CHISSO CORPORATION (JP) | 1995-07-04 | — | — | US | disclosed |
| US-5414126-A | Diamino compounds and liquid crystal aligning films | CHISSO CORPORATION (JP) | 1995-05-09 | — | — | US | disclosed |